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Wednesday, December 19th, 2018

 

New therapies could treat tissue swelling that afflicts cancer surgery patients and others

The lymphatic system starts to grow before birth and is fully formed by soon afterward. However, adults can produce new lymphatic vessels, a process termed lymphangiogenesis, after injuries. The drug Rockson’s group is studying blocks a lipid molecule, known as leukotriene B4, that curbs this regrowth. As Rockson and his colleagues reported last year inĀ Science Translational Medicine, lymphedema patients have high levels of the molecule. The scientists also found that low concentrations of the molecule induce new lymphatic vessels to sprout. Ubenimex knocks leukotriene B4’s concentration down to the progrowthRead More