Health Technologies

AI finds undiagnosed liver disease in early stages

A new study has revealed that an algorithm fuelled by artificial intelligence (AI) can accurately detect early-stage metabolic-associated steatotic liver disease (MASLD) by using electronic health records.

Liver disease, which is treatable when discovered early, often goes undetected until late stages.

Now, researchers have used an AI algorithm to analyse imaging findings in electronic health records from three sites within the University of Washington Medical System to identify patients who met the criteria for MASLD, the most common form of liver disease.

While 834 patients met the criteria, only 137 actually had an official MASLD-associated diagnosis in their record. This left 83 per cent of patients undiagnosed even when data in their electronic health record showed they met the criteria for MASLD.

“A significant proportion of patients who meet criteria for MASLD go undiagnosed,” said Ariana Stuart MD, a resident at University of Washington Internal Medicine Residency Program and lead author of the study.

“This is concerning because delays in early diagnosis increase the likelihood of progression to advanced liver disease.”

“People should not interpret our findings as a lack of primary care training or management,” Stuart said. “Instead, our study shows how AI can complement physician workflow to address the limitations of traditional clinical practice.”

MASLD occurs when fat isn’t managed properly in the liver and is often associated with other common diseases such as obesity, Type-2 diabetes, and abnormal cholesterol levels.

Early diagnosis of MASLD is key because it can quickly progress to more severe forms of liver disease, but many individuals in this early stage are asymptomatic, making diagnosis challenging.

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